Prospects of using nanopreparate “Сaplaestrol+OV” in veterinary reproductology

  • S. Y. Fedorenko Kharkiv State Zooveterinary Academy, Kharkiv
  • P. M. Sklyarov Dnipropetrovsk State Agrarian and Economic University, Dnipro
  • O. V. Khirna Center for Clinical Veterinary, Kharkiv
Keywords: reproductive pathologies, nanopreparate “Caplaestrol OV”, therapeutic and preventive measures

Abstract

The nanotechnology – one of the key areas of industrial development and progress of society. In veterinary medicine along with traditional chemical medicines for pets are increasingly being used bioactive therapy that complements the chemical treatment and is aimed at use of the body to regulate and drugs of natural origin.The positive results of the application of nanotechnology to encourage further research in veterinary medicine, particularly in the field of animal reproduction.The aim of research was to determine the effectiveness and prospects of nanopreparate “Caplaestrol+OV” in veterinary reproduction.It is known that under the influence of negative factors influence there is an imbalance in the system prooxidant-antioxidant oxidation and cytotoxic hypoxia, resulting in the pathological process at the cellular level. So it is logical to use materials that would impact on the prooxidant-antioxidant system and oxygen metabolism.Given this, in order to improve therapeutic efficacy “Caplaestrol+OV”, containing carotenoids and estrogens, focused on nanobiomaterials, in particular orthovanadate rare earth elements.Established that the use nanopreparat “Caplaestrol+OV” almost all the studied parameters reach values characteristic of animals with physiological constants. In general, a normalization of imbalance prooxidant-antioxidant system, as well as improvements in oxygen metabolism.In particular, in the way of normalization of the structure and function fetoplacental complex and increasing the development potential in the placenta of new-born experimental animals were no degenerative processes, significantly increased litter weight and total villous chorion area and mass concentration of maternal and neonatal immunoglobulins.The program of therapy animals with gonadodystrophy and hypogonadism is the restoration of the structure and function of the gonads, expression estrum and improving fertility and reducing the number of days of infertility.Thus, nanopreparat “Caplaestrol+OV” is effective for its use in therapeutic regimens and preventive measures for reproductive abnormalities farm animals and can be recommended for the practice of veterinary medicine.In the future, will be tested “Caplaestrol+OV” and other nanopreparats for the treatment and prevention of obstetric, gynecological and andrological diseases of small animals.

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Author Biographies

S. Y. Fedorenko, Kharkiv State Zooveterinary Academy, Kharkiv
к. вет. наук, доцент
P. M. Sklyarov, Dnipropetrovsk State Agrarian and Economic University, Dnipro
д. вет. наук, професор
O. V. Khirna, Center for Clinical Veterinary, Kharkiv
лікар ветеринарної медицини

References

Борисевич В. Б. Нанотехнологія у ветеринарній медицині / В. Б. Борисевич, О. Ф. Петренко ; ред. В. Б. Борисевич. – К. : Ліра, 2009. – 232 с.

Гнетнев А. М. Нанопрепараты серебра в хирургии и травматологии / А. М. Гнетнев, В. И. Рузанов, П. П. Родионов // Нанотехнологии и наноматериалы для биологии и медицины. – 2007. – Ч. 2. – С. 80–88.

Головенко М. Я. Наномедицина: досягнення і перспективи розвитку новітніх технологій у діагностиці та лікуванні / М. Я. Головенко // Журнал АМН України. – 2007. – Т. 13, № 4. – С. 1–23.

Девришов А. Д. Наночастицы для создания нових лекарственных форм / А. Д. Девришов // Ветеринарна медицина. – 2007. – № 4. – С. 3–4.

Здобутки нанотехнології в лікуванні та профілактиці хвороб тварин. Нановетеринарія (впровадження інноваційних технологій) / [В. Б. Борисевич, Б. В. Борисевич, Н. М. Хомин та ін.]; ред. В. Б. Борисевич. – К. : Ліра, 2009. – 182 с.

Комиссаренко А. А. Нанотехнологические аспекты ветеринарной гомеопатии / А. А. Комиссаренко, Т. В. Новосадюк // Ветеринария. – 2008. – № 7. – С. 50–53.

Липосомы и другие наночастицы как средство доставки лекарственных веществ / [А. П. Каплун, Ле Банг Шон, Ю. М. Краснопольский и др.]. ‒ Москва, 2005. – 258 с.

Нагорная Л. В. Наноматериалы – перспективы использования в ветеринарной медицине / Л. В. Нагорная // Научное обеспечение агропромышленного производства: Материалы Международной научно-практической конференции. – Курск, 2014. – С. 294–296.

Нанотехнологии и наноматериалы в ветеринарии [Электронный ресурс]. – Режим доступа : http://guv.tatarstan.ru/rus/file/pub/pub_95316.pdf

Перспективи застосування наночасток металів у ветеринарній медицині / [Н. О. Волошина, О. Ф. Петренко, В. Г. Каплуненко, М. В. Косінов] // Ветеринарна медицина України. – 2008. – № 9. – С. 32–34.

Перспективы нанотехнологии в вакцинопрофилактике / Т. В. Новосаднюк, А. А. Комисаренко, Э. Д. Джавадов, Н. Д. Придыбайло // Болезни птиц в промышленном птицеводстве. Современное состояние: проблемы и стратегия борьбы. – Санкт-Петербург, 2007. – С. 186-191.

Gupta Rohita. Applications of Nanoparticles in Veterinary Diagnostics, Therapeutics and Research / Rohita Gupta, Varsha Sharma // Journal of Immunology and Immunopathology. – 2016. – Volume 18, Issue 1. – P. 13–18.

Nano Science and Nanotechnology: Journey from Past to Present and Prospect in Veterinary Science and Medicine / S. Ganguly and S. K. Mukhopadhayay // International Journal of NanoScience and Nanotechnology. – 2011. – Vol. 2, № 1. – P. 79–83.

Nanomedicine: novel approaches in human and veterinary therapeutics / [J. M. Irache, I. Esparza, C. Gamazo et al.] // Veterinary Parasitology. – 2011. – Vol. 180. – P. 47–71.

Nanotechnology and its applications in Veterinary and Animal Science / S. S. Patil, K. B. Kore and P. Kumar // Veterinary World. – 2009. – Vol. 2 (12). – P. 475–477.

References

Borisevich, V. B., O. F. Petrenko (2009). Nanotechnology in veterinary medicine. Kyiv: Lira. 232 [in Ukraine].

Gnetnev A. M., Ruzanov V. I., Rodionov P. P. (2007). Nanopreparaty serebra v khirurgii i travmatologii. Nanotekhnologii i nanomaterialy dlya biologii i meditsiny, 2. 80–88 [in Russia].

Holovenko M. Y. (2007). Nanomedytsyna: dosyahnennya i perspektyvy rozvytku novitnikh tekhnolohiy u diahnostytsi ta likuvanni. Zhurnal Akademiyi medychnykh nauk Ukrayiny. 13, 4. 1–23 [in Ukraine].

Devryshov A. D. (2007). Nanochastitsy dlya sozdaniya novikh lekarstvennykh form. Veterinarna meditsina, 4. 3–4 [in Ukraine].

Borysevych V. B., Borysevych B. V., Khomyn N. M. et al. (2009). Zdobutky nanotekhnolohiyi v likuvanni ta profilaktytsi khvorob tvaryn. Nanoveterynariya (vprovadzhennya innovatsiynykh tekhnolohiy). Kyiv: Lira. 182 [in Ukraine].

Komyssarenko A. A., Novosadyuk T. V. (2008). Nanotekhnologicheskiye aspekty veterinarnoy gomeopatii. Veterinariya. 7. 50–53 [in Russia].

Kaplun A. P., Shon Le Banh, Krasnopolʹskyy Y. M. et al. (2005). Liposomy i drugiye nanochastitsy kak sredstvo dostavki lekarstvennykh veshchestv. Moskva. 258 [in Russia].

Nagornaya L. V. (2014). Nanomaterialy – perspektivy ispol'zovaniya v veterinarnoy meditsine. Nauchnoye obespecheniye agropromyshlennogo proizvodstva : Materialy Mezhdunarodnoy nauchno-prakticheskoy konferentsii. Kursk. 294–296 [in Russia].

Nanotekhnologii i nanomaterialy v veterinarii [Electronic resources]. – Access mode :

http://guv.tatarstan.ru/rus/file/pub/pub_95316.pdf [in Russia].

Voloshyna N. O., Petrenko O. F., Kaplunenko V. H., Kosinov M. V. (2008). Perspektyvy zastosuvannya nanochastok metaliv u veterynarniy medytsyn. Veterynarna medytsyna Ukrayiny. 9. 32–34 [in Ukraine].

Novosadnyuk T. V., Komysarenko A. A., Dzhavadov É. D., Prydybaylo N. D. (2007). Perspektivy nanotekhnologii v vaktsinoprofilaktike. Bolezni ptits v promyshlennom ptitsevodstve. Sovremennoye sostoyaniye: problemy i strategiya bor'by. Sankt-Peterburh. 186–191 [in Russia].

Gupta Rohita (2016). Applications of Nanoparticles in Veterinary Diagnostics, Therapeutics and Research. Journal of Immunology and Immunopathology. 18, 1. 13–18.

Ganguly S. and S. K. Mukhopadhayay (2011). Nano Science and Nanotechnology: Journey from Past to Present and Prospect in Veterinary Science and Medicine. International Journal of NanoScience and Nanotechnology. 2, 1. 79–83.

Irache J. M., Esparza I., Gamazo C. et al. (2011). Nanomedicine: novel approaches in human and veterinary therapeutics. Veterinary Parasitology. 180. 47–71.

Patil S. S., Kore K. B. and Kumar P. (2009). Nanotechnology and its applications in Veterinary and Animal Science. Veterinary World. 2 (12). 475–477


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How to Cite
Fedorenko, S., Sklyarov, P., & Khirna, O. (1). Prospects of using nanopreparate “Сaplaestrol+OV” in veterinary reproductology. Theoretical and Applied Veterinary Medicine, 5(2), 27-31. Retrieved from https://bulletin-biosafety.com/index.php/journal/article/view/106