TY - JOUR AU - A. Zamaziy PY - 2018/11/30 Y2 - 2024/03/29 TI - Hemocytopoiesis of functionally active newborn calves and calves in the state of hypoxia JF - Theoretical and Applied Veterinary Medicine JA - TAVM VL - 6 IS - 3 SE - Articles DO - 10.32819/2018.63009 UR - https://bulletin-biosafety.com/index.php/journal/article/view/198 AB - Fetal resistance to hypoxia is defined by its continuous affinity with the mother's body, and the transition of various substances depends on their concentration in the blood, the intensity of hemocirculation, and the permeability of cell membranes. We investigated the blood of functionally active newborn calves with signs of hypoxia, which were divided into three groups: І – animals in a state of asphyxia with meconium in the amniotic fluid (n = 9); ІІ – animals with inadequate spontaneous respiratory movements (n = 9); III – with spontaneous adequate respiratory movements (n = 9). The hematological analyzer was used to determine the dynamics of hemogram parameters and to calculate hematological indices during the first month of life. At the same time, we determined the indicators of hemo-, leuko- and thrombogram blood of cows pregnant with functionally active calves with signs of hypoxia. It has been established that a significant reduction in the number of red blood cells in calves' blood occurs in the first 5 days of life with an increase in the average volume of erythrocytes in the blood of functionally active calves by an average of 1.19 times (p < 0.01), a decrease in hemoglobin concentrations in erythrocyte especially in calves with low prenatal development. It should be noted that the above-mentioned processes in calves born with signs of hypoxia occur more "slowly" with the preservation of the dynamics inherent in functionally active calves. Hematologic indices allow to objectively determine qualitative and quantitative changes of concentrations and functional activity of leukocytes. In particular, there was a decrease during the neonatal period of LI, NLK and INS, and the growth of IP. Hemograms of cows, the mothers of functionally active and in the state of hypoxia newborn calves differ significantly. In the cows-mothers of functionally active newborn calves, the number of erythrocytes in the blood, hemoglobin and hematocrit content, the average content of platelets and thrombocyte were higher, while the average content of hemoglobin in the erythrocyte and the width of red blood cells distribution were higher in cows that gave birth to calves in a state of hypoxia. ER -