TY - JOUR AU - L. Shendryk AU - T. Akimenko AU - V. Salabay PY - 1970/01/01 Y2 - 2024/03/28 TI - THE INTEGRATED APPROACH TO THE DIAGNOSTICOF STRONGYLOIDOSIS OF CARNIVORES JF - Theoretical and Applied Veterinary Medicine JA - TAVM VL - 5 IS - 1 SE - Parasitology and Invasion Animal Diseases DO - UR - https://bulletin-biosafety.com/index.php/journal/article/view/91 AB - Background. The problem of the dogs` and cats`helminthiases, despite significant advances in science, it remains important in the veterinary practice and now without losing its relevance.The strongyloidosis as carnivorous disease, much less record that is likely due to the complexity of certain laboratory diagnostics as eggs pathogen - Strongyloidesstercoralis similar in structure to the eggs of intestinal hookworm (Ancylostoma sp. and Uncinaria sp.). Often, the diagnosis of helminthosesrelies onthe medical assumption at best - the scatological results of research that for some reasons is not always give final confirmation. Therefore, according to the researchers, the approach to diagnosis helminthes infestations should be comprehensive. Objective. Aim of our research was to assess the effectiveness of integrated diagnostic ofdogs`strongyloidosis. Methods. The researching was conducted at the veterinary clinic «ZooVetCenter» ofDnipro city, involving dogs, which found a violation of the bowel, dermatitis, especially on the face, belly and paws. From the laboratory methods used scatological research, as well as for early detection of pathogens invasion –hematologic (morphological and biochemical). Obligatorily, include epizootologicalinformation justifying the etiology of the disease. Results. Analysis of the epizootic situation in the service of the clinic, the results of processing statistical data reception animals in 2016, confirmed its areas of concern on invasive diseases. Helminthes dogs were registered in 11.7% of cases confirmed infestations of the whole year, with strongyloidiasis diagnosed in 7 animals was 2.8%. Our research was realized during the five months (from August to December 2016), which in addition to evaluation of wealth in the service area clinics included clinical examination, the results of scatological and hematological laboratory diagnostics, gave a somewhat different idea of the level of destruction helminthiases dogs in general and on strongyloidosis in particular. Thus, according to their research, with 127 dogs adopted during this period, 49 were affected by worms (38.6%) of them strongyloidosis found 26 dogs, representing 20.5% of all worms infested animals. This data is significantly different from the statistics obtained by the clinic. The scatology and the hematologywas realizedalong with the clinical researches. The researchesestablished the clinical changes in hematological parameters for that strongyloidosis. The various systems and organs of the body was involved in the pathological process, disrupting homeostasis. Conclusion. The strongyloyidos invasion confirmed in 20.5% of dogs. The highest EI noted in dogs under three months – 42.9%, the lowest – 6.1% – over 3 years. The second was the highest in puppies 2–4 months (34.3±1.7 eggs per 1 g of feces), and the lowest – in adult dogs – 14.4±2.3.The development of the pathological process in the organismof dogs strongyloidosis accompanied by changes in blood parameters: reduction in red blood cells – by 26.9%, decrease of the hemoglobin – by 10.5%, but the increase in the number of the white blood cells – the 36.3 % decrease of the total protein 26.6%, increasing in 1.5 times of total bilirubin and ALT activity of enzymes – AST and 2.4 – 1.7 times in comparison with indicators of healthy animals. ER -